Article
Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes.
American journal of medical genetics - 8 Dec 2001
Taylor A, Ezquerra M, Bagri G, Yip A, Goumidi L, Cottel D, Easton D, Evans J G, Xuereb J, Cairns N J, Amouyel P, Chartier-Harlin M C, Brayne C, Rubinsztein D C
Abstract excerpt
Hypertension has been implicated as a risk factor for Alzheimer disease (AD) and dementia in epidemiological studies of humans. It is thus possible that there are common genetic determinants for hypertension and AD. Epidemiological, clinical, and experimental data suggest that the renin-angiotensin-aldosterone system is a critical regulator of blood pressure. The presence of an MboI site in an RFLP in the renin...
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