Article
The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease.
Neuroscience letters - 16 Aug 2002
Lendon C L, Thaker U, Harris J M, McDonagh A M, Lambert J-C, Chartier-Harlin M-C, Iwatsubo T, Pickering-Brown S M, Mann D M A
Abstract excerpt
An insertion (I)/deletion (D) polymorphism in the angiotensin 1-converting enzyme (ACE) gene has, in some studies, been associated with increased risk for Alzheimer's disease (AD), and functionally the enzyme has been implicated in the degradation of amyloid beta protein (Abeta). We have investig...
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