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Article

A common variant of the ABO gene protects against hypertension in a Spanish population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jun 2012

Gassó Patricia, Mas Sergi, Álvarez Santiago, Ortiz Jacint, Sotoca Jose M, Francino Antonio, Carne Xavier, Lafuente Amalia

Abstract excerpt

The objective of this study was to establish whether genetic polymorphisms that could be related to angiotensin-converting enzyme (ACE) levels are associated with hypertension. A total of 10 haplotype-tagging single-nucleotide polymorphisms in ACE, the ACE I/D polymorphism, and 2 polymorphisms in the ABO (rs495828 and rs8176746) were investigated for association with hypertension in 269 hypertensive patients and...

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Source

Identifiers

PMID: 22258027
DOI: 10.1038/hr.2011.218

Genes

ABO
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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