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Article

Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2015

Chacon-Cortes Diego, Smith Robert A, Lea Rodney A, Youl Philippa H, Griffiths Lyn R

Abstract excerpt

Breast cancer incidence and mortality rates are increasing despite our current knowledge on the disease. Ninety-five percent of breast cancer cases correspond to sporadic forms of the disease and are believed to involve an interaction between environmental and genetic determinants. The microRNA 17-92 cluster host gene (MIR17HG) has been shown to regulate expression of genes involved in breast cancer development...

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PMID: 25680407
DOI: 10.1007/s13277-015-3200-1

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