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Article

NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans.

Human genetics - 1 Nov 2009

Velez Digna Rosa, Hulme William F, Myers Jamie L, Weinberg J Brice, Levesque Marc C, Stryjewski Martin E, Abbate Eduardo, Estevan Rosa, Patillo Sara G, Gilbert John R, Hamilton Carol D, Scott William K

Abstract excerpt

Tuberculosis (TB) has substantial mortality worldwide with 5-10% of those exposed progressing to active TB disease. Studies in mice and humans indicate that the inducible nitric oxide synthase (iNOS) molecule plays an important role in immune response to TB. A mixed case-control association study of individuals with TB, relatives, or close contact controls was performed in 726 individuals (279 case and 166...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interferon gamma Receptor

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Share to Receptors, Interferon

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Share to Tuberculosis, Pulmonary

Source

Open in PubMed Open full text

Identifiers

PMID: 19575238
DOI: 10.1007/s00439-009-0713-y
PMCID: PMC2881538

Genes

IFNGR1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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