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Article

Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast.

Molecular biology of the cell - 1 Apr 2015

Johnson Courtney R, Weems Andrew D, Brewer Jennifer M, Thorner Jeremy, McMurray Michael A

Abstract excerpt

Septin hetero-oligomers polymerize into cytoskeletal filaments with essential functions in many eukaryotic cell types. Mutations within the oligomerization interface that encompasses the GTP-binding pocket of a septin (its "G interface") cause thermoinstability of yeast septin hetero-oligomer assembly, and human disease. When coexpressed with its wild-type counterpart, a G interface mutant is excluded from septin...

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Identifiers

PMID: 25673805
DOI: 10.1091/mbc.E14-11-1531
PMCID: PMC4454179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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