Article

Interface integrity in septin protofilaments is maintained by an arginine residue conserved from yeast to man

2025-01-29

Abstract excerpt

The septins are conserved, filament-forming, guanine nucleotide binding cytoskeletal proteins. They assemble into palindromic protofilaments which polymerize further into higher-ordered structures that participate in essential intracellular processes such as cytokinesis or polarity establishment. Septins belong structurally to the P-Loop NTPases but, unlike their relatives Ras or Rho, do not mediate signals to eff...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 055d8ff9-cadd-54c8-b4d9-89e3372aaaa6
DOI: 10.1101/2025.01.29.635471

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interface integrity in septin protofilaments is maintained by an arginine residue conserved from yeast to manDOI 10.1101/2025.01.29.635471Read

An <i>in silico</i> approach to determine inter-subunit affinities in human septin complexesSemantic proximity Read

A Key Piece of the Puzzle: The central tetramer of the <i>Saccharomyces cerevisiae</i> septin protofilament and Its Implications for Self-AssemblySemantic proximity Read

Control of septin filament flexibility and bundling by subunit composition and nucleotide interactions.Semantic proximity Read

Synergistic role of nucleotides and lipids for the self-assembly of Shs1 septin oligomers.Semantic proximity Read

Conquering the complex world of human septins: implications for health and disease.Semantic proximity Read

Uncovering principles that control septin-septin interactions.Semantic proximity Read

Higher-order septin assembly is driven by GTP-promoted conformational changes: evidence from unbiased mutational analysis in Saccharomyces cerevisiae.Semantic proximity Read

A Draft of the Human Septin InteractomeSemantic proximity Read

A specific mesh-like organization of human septin octameric complex drives membrane reshaping and curvature sensitivitySemantic proximity Read

Chaperone Requirements for De Novo Folding of <i>Saccharomyces cerevisiae</i> SeptinsSemantic proximity Read

A FRET-based method for monitoring septin polymerization and binding of septin-associated proteins.Semantic proximity Read

Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast.Semantic proximity Read