Article
A systems genetics approach to dyslipidemia in children and adolescents.
Omics : a journal of integrative biology - 1 Apr 2015
White Marquitta J, Eren Fatih, Ağırbaşlı Deniz, Chen Jane, Hu Ting, Moore Jason H, Williams Scott M, Ağırbaşlı Mehmet
Abstract excerpt
Elevated triglycerides (TG) or low high density lipoprotein cholesterol (HDL-C) levels are common cardiometabolic risk factors in children. From a systems genetics standpoint, Visualization of Statistical Epistasis Networks (ViSEN) is a nonparametric entropy-based method that can characterize the global structure of interacting genetic factors. We identified a novel set of connected genetic and cardiometabolic...
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