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Article

Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children.

PloS one - 1 Jan 2015

Breitling Clara, Gross Arnd, Büttner Petra, Weise Sebastian, Schleinitz Dorit, Kiess Wieland, Scholz Markus, Kovacs Peter, Körner Antje

Abstract excerpt

OBJECTIVE: To assess potential effects of variants in six lipid modulating genes (SORT1, HMGCR, MLXIPL, FADS2, APOE and MAFB) on early development of dyslipidemia independent of the degree of obesity in children, we investigated their association with total (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C) cholesterol and triglyceride (TG) levels in 594 children. Furthermore, we evaluated...

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Share to Adaptor Proteins, Vesicular Transport
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26375028
DOI: 10.1371/journal.pone.0138064
PMCID: PMC4573320

Genes

APOE
SORT1
FADS2
HMGCR
MAFB
MLXIPL
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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