Article
Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura.
PloS one - 1 Jan 2015
Edgar Contessa E, Terrell Deirdra R, Vesely Sara K, Wren Jonathan D, Dozmorov Igor M, Niewold Timothy B, Brown Michael, Zhou Fang, Frank Mark Barton, Merrill Joan T, Kremer Hovinga Johanna A, Lämmle Bernhard, James Judith A, George James N, Farris A Darise
Abstract excerpt
Approximately 40% of patients who survive acute episodes of thrombotic thrombocytopenic purpura (TTP) associated with severe acquired ADAMTS13 deficiency experience one or more relapses. Risk factors for relapse other than severe ADAMTS13 deficiency and ADAMTS13 autoantibodies are unknown. ADAMTS13 autoantibodies, TTP episodes following infection or type I interferon treatment and reported ensuing systemic lupus...
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