Article
The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis.
Neurobiology of aging - 1 Apr 2015
Gang Qiang, Bettencourt Conceicao, Machado Pedro M, Fox Zoe, Brady Stefen, Healy Estelle, Parton Matt, Holton Janice L, Hilton-Jones David, Shieh Perry B, Zanoteli Edmar, De Paepe Boel, De Bleecker Jan, Shaibani Aziz, Ripolone Michela, Violano Raffaella, Moggio Maurizio, Barohn Richard J, Dimachkie Mazen M, Mora Marina, Mantegazza Renato, Zanotti Simona, Hanna Michael G, Houlden Henry
Abstract excerpt
A previous study showed that, in carriers of the apolipoprotein E (APOE) genotype ε3/ε3 or ε3/ε4, the presence of a very long (VL) polyT repeat allele in "translocase of outer mitochondrial membrane 40" (TOMM40) was less frequent in patients with sporadic inclusion body myositis (sIBM) compared w...
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