Article
Distribution of the HLA class I allele in chronic hepatitis C and its association with serum ALT level in chronic hepatitis C.
The Tohoku journal of experimental medicine - 1 Oct 2003
Kondo Yasuteru, Kobayashi Koju, Kobayashi Tomoo, Shiina Masaaki, Ueno Yoshiyuki, Satoh Takaomi, Shimosegawa Tooru
Abstract excerpt
An essential process for resolution of viral infections is the efficient recognition and elimination of intracellular virus. Recognition of viral antigens in the form of short peptides associated with HLA class I molecule is a major task of CD8+ cytotoxic T lymphocytes. In this study, we have evaluated the frequency of the HLA class I alleles in patients with chronic hepatitis C. HLA-B51, -B52, -B55, -B56, -B61,...
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