Article
GermLine Variation in Superoxide Dismutase-2 (SOD2) and Survival Outcomes After Radiation Therapy for Prostate Cancer: Results of a Test and Validation Set Analysis.
Clinical genitourinary cancer - 1 Aug 2015
Margalit Danielle N, Jordahl Kristina M, Werner Lillian, Wang Xiaodong, Gwo-Shu Lee Mary, Penney Kathryn L, Batista Julie L, Martin Neil E, Chan June M, Kantoff Philip W, Stampfer Meir J, Nguyen Paul L, Mucci Lorelei A
Abstract excerpt
BACKGROUND: Genetic variants in antioxidant pathways might decrease the efficacy of radiation therapy (RT) by suppressing the generation of reactive oxygen species. We studied the association between single nucleotide polymorphisms (SNPs) in the antioxidant gene superoxide dismutase-2 (SOD2) and cancer-specific outcomes after RT. PATIENTS AND METHODS: Among 816 prostate cancer patients who received radiation as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.