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Article

A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2013

Schoenfeld Jonathan D, Margalit Danielle N, Kasperzyk Julie L, Shui Irene M, Rider Jennifer R, Epstein Mara M, Meisner Allison, Kenfield Stacey A, Martin Neil E, Nguyen Paul L, Kantoff Philip W, Giovannucci Edward L, Stampfer Meir J, Mucci Lorelei A

Abstract excerpt

PURPOSE: To study associations between single nucleotide polymorphisms (SNP) in Ribonuclease L (RNASEL), a gene implicated in inflammation and prostate cancer risk, and outcomes after radiation therapy. EXPERIMENTAL DESIGN: We followed participants in the prospective US Health Professionals Follow-Up Study treated with radiation therapy for early-stage prostate cancer. Three SNPs were genotyped based on...

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Identifiers

PMID: 23382116
DOI: 10.1158/1078-0432.CCR-12-2718
PMCID: PMC3602407

Genes

RNASEL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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