Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational profile of KIT and PDGFRA genes in gastrointestinal stromal tumors in Peruvian samples.

Revista espanola de enfermedades digestivas - 1 Feb 2015

Buleje José, Acosta Óscar, Guevara-Fujita María, Enriquez Yanina, Taxa Luis, Machicado Enrique, Lizaraso-Caparó Frank, Fujita Ricardo

Abstract excerpt

INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms usually caused by somatic mutations in the genes KIT (c-kit) or PDGFRA. Mutation characterization has become an important exam for GIST patients because it is useful in predicting the response to the inhibitors of receptor tyrosine kinase (RTK). OBJECTIVES: The aim of this study was to determine the frequency of KIT and PDGFRA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Neoplasms

Share to Gastrointestinal Stromal Tumors

Share to Mutation

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Platelet-Derived Growth Factor alpha

Source

Identifiers

PMID: 25659388

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational profile of KIT and PDGFRA genes in gastrointestinal stromal tumors in Peruvian samples.PMID 25659388Read ↗

Somatic mutational spectrum analysis in a prospective series of 104 gastrointestinal stromal tumors.Semantic proximity Read ↗

KIT and PDGFRA mutations and PDGFRA immunostaining in gastrointestinal stromal tumors.Semantic proximity Read ↗

Analysis of mutation of the c-Kit gene and PDGFRA in gastrointestinal stromal tumorsSemantic proximity Read ↗

The analysis of status and clinical implication of KIT and PDGFRA mutations in gastrointestinal stromal tumor (GIST).Semantic proximity Read ↗

Molecular alterations of KIT and PDGFRA in GISTs: evaluation of a Portuguese seriesSemantic proximity Read ↗

KIT and PDGFRa mutational patterns in Sardinian patients with gastrointestinal stromal tumors.Semantic proximity Read ↗

Mutations of the c-Kit and PDGFRA gene in gastrointestinal stromal tumors among hakka population of Southern China.Semantic proximity Read ↗

Spectrum of mutations in gastrointestinal stromal tumor patients - a population-based study from Slovakia.Semantic proximity Read ↗

KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs).Semantic proximity Read ↗

Comprehensive molecular screening by next generation sequencing reveals a distinctive mutational profile of KIT/PDGFRA genes and novel genomic alterations: results from a 20-year cohort of patients with GIST from north-western GreeceSemantic proximity Read ↗

Epidemiology and molecular biology of gastrointestinal stromal tumors (GISTs): a population-based study in the South of Switzerland, 1999-2005.Semantic proximity Read ↗

Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.