Article
HLA-A*33:01 as protective allele for severe dengue in a population of Filipino children.
PloS one - 1 Jan 2015
Mercado Edelwisa Segubre, Espino Fe Esperanza, Perez Ma Lucila M, Bilar Josie M, Bajaro Jemimah Dawn P, Huy Nguyen Tien, Baello Benilda Q, Kikuchi Mihoko, Hirayama Kenji
Abstract excerpt
Dengue virus infection is a leading cause of morbidity among children in the Philippines in recent years. In order to investigate the association of HLA Class I and II alleles and dengue disease severity in a cohort of Filipino children, we performed a case control study in 2 hospitals in Metro Manila from June 2008 to December 2009. A total of 250 laboratory confirmed dengue patients and 300 healthy individuals...
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