Article
HLA-A*01 allele: a risk factor for dengue haemorrhagic fever in Brazil's population.
Memorias do Instituto Oswaldo Cruz - 1 Mar 2012
Monteiro Sérgio Pereira, Brasil Pedro Emmanuel Alvarenga Americano do, Cabello Giselda Maria Kalil, Souza Rogério Valls de, Brasil Patrícia, Georg Ingebourg, Cabello Pedro Hernan, De Castro Liane
Abstract excerpt
Severe forms of dengue, such as dengue haemorrhagic fever (DHF) and dengue shock syndrome, are examples of a complex pathogenic mechanism in which the virus, environment and host immune response interact. The influence of the host's genetic predisposition to susceptibility or resistance to infectious diseases has been evidenced in several studies. The association of the human leukocyte antigen gene (HLA) class I...
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