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Article

Association between IL13 gene polymorphisms and susceptibility to cancer: a meta-analysis.

Gene - 15 Feb 2013

Su Tong, Mi Yuanyuan, Zhang Lifeng, Wang Shangqian, Lu Hongbiao, Shi Li, Sun Heyun, Wu Xiaopeng, Zhang Wei, Zuo Li, Zou Jiangang

Abstract excerpt

BACKGROUND/AIMS: Interleukin-13 (IL13) is an immunoregulatory cytokine which plays an important role in carcinogenesis through affecting tumor immunosurveillance. Many studies had reported the influence of IL13 rs1800925 and rs20541 polymorphisms on cancer risk, however, with inconclusive results. The aim of the present study was to conduct a meta-analysis to clarify the relationship. METHODS: Twenty studies...

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PMID: 23246181
DOI: 10.1016/j.gene.2012.11.035

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