Article
IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population.
International journal of cancer - 1 Apr 2011
Liu Li, Xu Yan, Liu Zheng, Chen Jianguo, Zhang Yixin, Zhu Jian, Liu Jibin, Liu Sheng, Ji Guozhong, Shi Haibin, Shen Hongbing, Hu Zhibin
Abstract excerpt
To investigate the association between the potentially functional polymorphisms in IL12A and IL12B, HBV infection and risk of hepatocellular carcinoma in a Chinese population, we genotyped three polymorphisms, rs568408 (3'UTR G>A), rs2243115 (5'UTR T>G) in IL12A and rs3212227 (3'UTR A>C) in IL12B in a case-control study of 869 hepatocellular carcinoma (HCC) cases and 891 cancer-free controls. We found that the...
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