Article
Prognostic significance of CpG island methylator phenotype in surgically resected small cell lung carcinoma.
Cancer science - 1 Mar 2016
Saito Yuichi, Nagae Genta, Motoi Noriko, Miyauchi Eisaku, Ninomiya Hironori, Uehara Hirofumi, Mun Mingyon, Okumura Sakae, Ohyanagi Fumiyoshi, Nishio Makoto, Satoh Yukitoshi, Aburatani Hiroyuki, Ishikawa Yuichi
Abstract excerpt
Methylation is closely involved in the development of various carcinomas. However, few datasets are available for small cell lung cancer (SCLC) due to the scarcity of fresh tumor samples. The aim of the present study is to clarify relationships between clinicopathological features and results of the comprehensive genome-wide methylation profile of SCLC. We investigated the genome-wide DNA methylation status of 28...
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