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Methods of Random Mutagenesis of Aspergillus Strain for Increasing Kojic Acid Production.

Current pharmaceutical biotechnology - 1 Jan 2022

Suryadi Herman, Irianti Marina Ika, Septiarini Tri Hastuti

Abstract excerpt

Kojic acid is an organic acid that is commonly used in the pharmaceutical and cosmetic industries. This acid compound is a secondary metabolite produced by various microorganisms, one of which is Aspergillus oryzae. Typically, improving the strain can enhance kojic acid production. A mutation is one of the tools to perform strain improvement because the change in kojic acidproducing genes effectively increases...

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PMID: 34132182
DOI: 10.2174/1389201022666210615125004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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