Article
MS-HRM assay identifies high levels of epigenetic heterogeneity in human immortalized cell lines.
Gene - 15 Apr 2015
Putnik Milica, Wojdacz Tomasz K, Pournara Angeliki, Vahter Marie, Wallberg Annika E
Abstract excerpt
Immortalized cell lines are widely used in genetic and epigenetic studies, from exploration of basic molecular pathways to evaluation of disease-specific cellular properties. They are also used in biotechnology, e.g., in drug toxicity tests and vaccine production. Cellular and genetic uniformity...
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