Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of IL28B and PNPLA3 polymorphisms on treatment outcomes in patients infected with genotype 6 hepatitis C virus.

Journal of gastroenterology and hepatology - 1 Jun 2015

Wong Grace Lai-Hung, Chan Henry Lik-Yuen, Tse Chi-Hang, Chan Polly Oi-Ying, Cheng Joe Cho-Yiu, Cheng Jackie Siu-Woon, Lau Sharon Hoi-Ying, Lee Elbert Kam-Yeung, Ma Justin Ming-Yin, Chan Anthony Wing-Hung, Choi Paul Cheung-Lung, Wong Vincent Wai-Sun

Abstract excerpt

BACKGROUND/AIMS: Interleukin-28B (IL28B) and patatin-like phospholipase domain containing 3 (PNPLA3) gene polymorphisms are associated with hepatitis C virus (HCV) clearance and fatty liver, respectively. We aimed to test if their polymorphisms are associated with virologic responses in Chinese chronic hepatitis C (CHC) patients. METHODS: This was a retrospective-prospective cohort study. Consecutive patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C

Share to Interferons

Share to Interleukins

Share to Lipase

Share to Treatment Outcome

Source

Identifiers

PMID: 25639146
DOI: 10.1111/jgh.12890

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of IL28B and PNPLA3 polymorphisms on treatment outcomes in patients infected with genotype 6 hepatitis C virus.PMID 25639146Read ↗

Impact of IL28B, ITPA and PNPLA3 genetic variants on therapeutic outcome and progression of hepatitis C virus infection.Semantic proximity Read ↗

Prevalence of IL-28B and ITPA genotypes in Chinese Han population infected persistently with hepatitis C virus genotype 6 or HCV-1.Semantic proximity Read ↗

Evaluation of the association of a variant in PNPLA3 and TM6SF2 with fibrosis progression in patients with chronic hepatitis C infection after eradication: A retrospective study.Semantic proximity Read ↗

PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.Semantic proximity Read ↗

Distribution and clinical correlates of viral and host genotypes in Chinese patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

SVR Rates of HCV-infected population under PEG-IFN-α/R treatment in Northwest China.Semantic proximity Read ↗

Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens.Semantic proximity Read ↗

IL28B SNP rs12979860 is the Critical Predictor for Sustained Viral Response in Chinese Children Aged 1 to 6 Years with Chronic Hepatitis C.Semantic proximity Read ↗

Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication.Semantic proximity Read ↗

Impact of comorbid hepatic steatosis on treatment of chronic hepatitis C in Japanese patients and the relationship with genetic polymorphism of IL28B, PNPLA3 and LDL receptor.Semantic proximity Read ↗

Pretreatment Predictors of Response to PegIFN-RBV Therapy in Egyptian Patients with HCV Genotype 4.Semantic proximity Read ↗

Impact of IL28 Genotypes and Modeling the Interactions of HCV Core Protein on Treatment of Hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.