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Article

Impact of IL28 Genotypes and Modeling the Interactions of HCV Core Protein on Treatment of Hepatitis C.

Interdisciplinary sciences, computational life sciences - 1 Dec 2020

Hashempour Tayebeh, Dehghani Behzad, Musavi Zahra, Moayedi Javad, Hasanshahi Zahra, Sarvari Jamal, Hosseini Seyed Younes, Hosseini Ebrahim, Moeini Maryam, Merat Shahin

Abstract excerpt

BACKGROUND: Mutations in the core CVR region of hepatitis C virus (HCV) and polymorphisms of interleukin 28B (IL28B) are associated with progression toward liver disease and in response to therapy. In addition, interactions of the core protein with some cell interactors can be related to HCV liver damage. AIM: This study aimed to evaluate the effect of core mutations as well as IL28B polymorphism on clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32656614
DOI: 10.1007/s12539-020-00382-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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