Article
Positive immunohistochemical staining of KIT in solid-pseudopapillary neoplasms of the pancreas is not associated with KIT/PDGFRA mutations.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2006
Cao Dengfeng, Antonescu Cristina, Wong Grace, Winter Jordan, Maitra Anirban, Adsay N Volkan, Klimstra David S, Hruban Ralph H
Abstract excerpt
Solid-pseudopapillary neoplasms of the pancreas are uncommon neoplasms of low malignant potential and of uncertain histogenesis. A small percentage of patients develop metastatic disease and some succumb to disease. The management of patients with metastatic disease or unresectable tumor, and patients who are just not good surgical candidates is problematic. Novel therapy targets are needed. Successful treatment...
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