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Article

A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1.

Diabetologia - 1 Apr 2015

Locke Jonathan M, Wei Fan-Yan, Tomizawa Kazuhito, Weedon Michael N, Harries Lorna W

Abstract excerpt

AIMS/HYPOTHESIS: Intronic single nucleotide polymorphisms (SNPs) in the CDKAL1 gene are associated with risk of developing type 2 diabetes. A strong correlation between risk alleles and lower levels of the non-coding RNA, CDKAL1-v1, has recently been reported in whole blood extracted from Japanes...

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Identifiers

PMID: 25634229
DOI: 10.1007/s00125-015-3508-9
PMCID: PMC4351432

Genes

CDKAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25634229-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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