Article
Lack of association between interleukin-10, transforming growth factor-beta gene polymorphisms and juvenile-onset systemic lupus erythematosus.
Clinical rheumatology - 1 Jun 2015
Rezaei Arezou, Ziaee Vahid, Sharabian Fatemeh Tahghighi, Harsini Sara, Mahmoudi Maryam, Soltani Samaneh, Sadr Maryam, Moradinejad Mohammad Hassan, Aghighi Yahya, Rezaei Nima
Abstract excerpt
As abundant types of genetic predisposition and environmental factors seem to be associated with the development of juvenile-onset systemic lupus erythematosus (JSLE), we investigated the gene polymorphisms of two anti-inflammatory cytokines, including interleukin-10 (IL-10) and transforming growth factor-beta (TGF-β), which were previously found to be associated with SLE in adults, in a group of patients with...
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