Article
An RNAi-Based Candidate Screen for Modifiers of the CHD1 Chromatin Remodeler and Assembly Factor in Drosophila melanogaster.
G3 (Bethesda, Md.) - 23 Nov 2015
Kim Sharon, Bugga Lakshmi, Hong Eugenie S, Zabinsky Rebecca, Edwards Rebecca G, Deodhar Parimal A, Armstrong Jennifer A
Abstract excerpt
The conserved chromatin remodeling and assembly factor CHD1 (chromodomains, helicase, DNA-binding domain) is present at active genes where it participates in histone turnover and recycling during transcription. In order to gain a more complete understanding of the mechanism of action of CHD1 during development, we created a novel genetic assay in Drosophila melanogaster to evaluate potential functional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
