Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of human arylamine <i>N</i>‐acetyltransferase I knockdown in triple‐negative breast cancer cell lines

28 Jan 2015

Abstract excerpt

Expression of human arylamine N-acetyltransferase I (NAT1) has been associated with various cancer subtypes and inhibition of this enzyme with small molecule inhibitors or siRNA affects cell growth and survival. Here, we have investigated the role of NAT1 in the invasiveness of breast cancer cells both in vitro and in vivo. We knocked down NAT1 using a lentivirus-based shRNA approach and observed marked changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Mass Spectrometry Techniques and Applications
Share to Polyamine Metabolism and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25627111
DOI: 10.1002/cam4.415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of human arylamine <i>N</i>‐acetyltransferase I knockdown in triple‐negative breast cancer cell linesPMID 25627111Read ↗

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistanceSemantic proximity Read ↗

Regulation of arylamine N-acetyltransferases.Semantic proximity Read ↗

Depletion of the human N<sup>α</sup>‐terminal acetyltransferase A induces p53‐dependent apoptosis and p53‐independent growth inhibitionSemantic proximity Read ↗

N-Acetyltransferase 10 Enhances Doxorubicin Resistance in Human Hepatocellular Carcinoma Cell Lines by Promoting the Epithelial-to-Mesenchymal TransitionSemantic proximity Read ↗

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transitionSemantic proximity Read ↗

Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct.Semantic proximity Read ↗

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities.Semantic proximity Read ↗

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stabilitySemantic proximity Read ↗

Thiosemicarbazone T2 suppresses WNT/β-catenin signaling and limits progression to invasive disease in a mouse intraductal model of triple-negative breast cancerSemantic proximity Read ↗

Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases.Semantic proximity Read ↗

Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells.Semantic proximity Read ↗

A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial–Mesenchymal Transition and Metastatic DisseminationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.