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Article

Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population.

BMC pediatrics - 26 Jan 2024

Fan Juan, He Hua-Yun, Li Huan-Huan, Wu Pi-Liu, Tang Lei, Deng Bo-Yin, Dong Wen-Hui, Wang Jian-Hui

Abstract excerpt

BACKGROUND: Severe neonatal hyperbilirubinemia could lead to kernicterus and neonatal death. This study aimed to analyze the association between single nucleotide polymorphisms in genes involved in bilirubin metabolism and the incidence of severe hyperbilirubinemia. METHODS: A total of 144 neonates with severe hyperbilirubinemia and 50 neonates without or mild hyperbilirubinemia were enrolled in 3 institutions...

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Source

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Identifiers

PMID: 38279097
DOI: 10.1186/s12887-024-04537-0
PMCID: PMC10811893

Genes

UGT1A1
SLCO1B3
BLVRA
HMOX1
SLCO1B1
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Research trail→

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Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population.PMID 38279097Read ↗

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