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Article

Candidate gene analysis of BRCA1/2 mutation-negative high-risk Russian breast cancer patients.

Cancer letters - 10 Apr 2015

Sokolenko Anna P, Preobrazhenskaya Elena V, Aleksakhina Svetlana N, Iyevleva Aglaya G, Mitiushkina Natalia V, Zaitseva Olga A, Yatsuk Olga S, Tiurin Vladislav I, Strelkova Tatiana N, Togo Alexandr V, Imyanitov Evgeny N

Abstract excerpt

Twenty one DNA repair genes were analyzed in a group of 95 BC patients, who displayed clinical features of hereditary disease predisposition but turned out to be negative for mutations in BRCA1 and BRCA2 entire coding region as well as for founder disease-predisposing alleles in CHEK2, NBN/NBS1 and ATM genes. Full-length sequencing of CHEK2 and NBN/NBS1 failed to identify non-founder mutations. The analysis of...

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Source

Identifiers

PMID: 25619955
DOI: 10.1016/j.canlet.2015.01.022

Genes

WRN
BRCA1
CHEK2
NBN
ATM
BARD1
BLM
BRCA2
BRD7
BRIP1
CHEK1
DDB2
ERCC1
EXO1
FANCC
FANCG
PALB2
PARP1
PARP2
RAD51
RNF8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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