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Article

Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial‐to‐mesenchymal transition

6 Jan 2015

Abstract excerpt

Peritoneal dissemination is a major clinical obstacle in gastrointestinal cancer therapy, and it accounts for the majority of cancer-related mortality. Calreticulin (CRT) is over-expressed in gastric tumors and has been linked to poor prognosis. In this study, immunohistochemistry studies revealed that the up-regulation of CRT was associated with lymph node and distant metastasis in patients with gastric cancer...

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Identifiers

PMID: 25619450
DOI: 10.1016/j.molonc.2014.12.009

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