Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global Promoter Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes in Natural Killer Cell Lymphoma

23 Jan 2015

Abstract excerpt

PURPOSE: To identify tumor suppressor genes epigenetically silenced by promoter hypermethylation in extranodal natural killer cell lymphoma (NKCL). EXPERIMENTAL DESIGN: Promoter methylation was analyzed with global and locus-specific methylation assays in NKCL cases and NK cell lines. Gene expression profiles were used to identify genes for which aberrant promoter methylation was associated with transcriptional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25614448
DOI: 10.1158/1078-0432.ccr-14-1216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global Promoter Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes in Natural Killer Cell LymphomaPMID 25614448Read ↗

Frequent Mutations in Natural Killer/T Cell Lymphoma.Semantic proximity Read ↗

The Genomics and Molecular Biology of Natural Killer/T-Cell Lymphoma: Opportunities for TranslationSemantic proximity Read ↗

The Pathologic and Genetic Characteristics of Extranodal NK/T-Cell LymphomaSemantic proximity Read ↗

Hypermethylation of PRDM1/Blimp-1 promoter in extranodal NK/T-cell lymphoma, nasal type: an evidence of predominant role in its downregulation.Semantic proximity Read ↗

Epigenetic silencing of multiple genes in primary CNS lymphomaSemantic proximity Read ↗

Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell LymphomaSemantic proximity Read ↗

IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression.Semantic proximity Read ↗

Frequent mutations in HLA and related genes in extranodal NK/T cell lymphomas.Semantic proximity Read ↗

Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas.Semantic proximity Read ↗

Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomasSemantic proximity Read ↗

DNA methylation maintains allele-specific KIR gene expression in human natural killer cells.Semantic proximity Read ↗

Multiomics analysis reveals the genetic and epigenetic features of high-risk NK cell–type chronic active EBV infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.