Article
A dysregulated microRNA-26a/EphA2 axis impairs endothelial progenitor cell function via the p38 MAPK/VEGF pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Zuo Keqiang, Zhi Kangkang, Zhang Xiaoping, Lu Chenghui, Wang Shi, Li Maoquan, He Bin
Abstract excerpt
BACKGROUND: Dysfunction of circulating endothelial progenitor cells (EPCs) is associated with the onset of cardiovascular disorders. Circulating microRNAs (miRNAs) have been recognized as novel biomarkers and potential therapeutic targets. Here, we examined the role of miR-26a overexpression in atherosclerosis and explored the underlying mechanisms. METHODS: EPCs were obtained from patients with atherosclerosis...
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