Article
AngiomiRs--key regulators of angiogenesis.
Current opinion in genetics & development - 1 Jun 2009
Wang Shusheng, Olson Eric N
Abstract excerpt
The formation of new blood vessels through the process of angiogenesis is critical in vascular development and homeostasis. Aberrant angiogenesis leads to a variety of diseases, such as ischemia and cancer. Recent studies have revealed important roles for miRNAs in regulating endothelial cell (EC) function, especially angiogenesis. Mice with EC-specific deletion of Dicer, a key enzyme for generating miRNAs,...
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