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Article

Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease.

PloS one - 1 Jan 2015

Chand Sourabh, Chue Colin D, Edwards Nicola C, Hodson James, Simmonds Matthew J, Hamilton Alexander, Gough Stephen C L, Harper Lorraine, Steeds Rick P, Townend Jonathan N, Ferro Charles J, Borrows Richard

Abstract excerpt

BACKGROUND: Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease and heart failure. Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst patients with established heart failure and in patients with progression of their renal disease. The association of a cardiac functional difference in...

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C-Reactive Protein
Cholesterol
Magnetic Resonance Imaging
Nitric Oxide Synthase Type III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Renal Insufficiency, Chronic

Ventricular Function, Left

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PMID: 25612295
DOI: 10.1371/journal.pone.0116160
PMCID: PMC4303420

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