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Endothelial nitric oxide synthase gene intron4 VNTR polymorphism in patients with chronic kidney disease.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2011

Elshamaa Manal F, Sabry Samar, Badr Ahmed, El-Ahmady Mostafa, Elghoroury Eman A, Thabet Eman H, Kandil Dina, Kamel Solaf

Abstract excerpt

Nitric oxide production is reduced in renal disease, partially due to decreased endothelial nitric oxide production. Evidence indicates that nitric oxide deficiency contributes to cardiovascular events and progression of kidney damage. A polymorphism in intron 4 of the endothelial constitutive nitric oxide synthase (ecNOS) gene is a candidate gene in cardiovascular and renal diseases. We investigated a potential...

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PMID: 21519233
DOI: 10.1097/MBC.0b013e328346ef71

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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