Article
SOX11 expression in chronic lymphocytic leukemia correlates with adverse prognostic markers.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2015
Roisman Alejandro, Stanganelli Carmen, Nagore Virginia Palau, Richardson Guillermo Videla, Scassa María Elida, Bezares Raimundo Fernando, Cabrejo María, Slavutsky Irma
Abstract excerpt
The transcription factor SOX11 plays an important role in embryonic neurogenesis and tissue remodeling. Recent studies have shown aberrant expression of SOX11 in various types of aggressive B cell neoplasms. In this study, we have analyzed SOX11 transcription levels in 86 patients with diagnosis of chronic lymphocytic leukemia (CLL). Results were correlated with well-known prognostic factors such as...
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