Article
Development of DO*A and DO*B Allele Detections to Predict Transfusion-Induced Alloimmunization Risks in Thai Populations.
Clinical laboratory - 1 Oct 2021
Wangmo Tshering, Intharanut Kamphon, Leetrakool Nipapan, Mitundee Supattra, Bejrachandra Sasitorn, Nathalang Oytip
Abstract excerpt
BACKGROUND: Two antithetical antigens, Doa and Dob of the Dombrock (DO) blood group system are implicated in acute to delayed hemolytic transfusion reactions among patients with anti-Doa or anti-Dob. Given the unavailability of specific antiserum, a polymerase chain reaction with sequence-specific primer (PCR-SSP) was developed to identify DO*A and DO*B alleles. This study aimed to determine DO*A and DO*B allele...
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