Article
HNA-1, -3, -4, and -5 genotyping using multiplex PCR among southern Thais: Developing continual HNA-1 null detection.
Journal of clinical laboratory analysis - 1 Jan 2019
Intharanut Kamphon, Sasikarn Wiradee, Mitundee Supattra, Nathalang Oytip
Abstract excerpt
BACKGROUND: Antibodies against human neutrophil antigens (HNAs) are involved in various clinical conditions including transfusion-related acute lung injury and auto/alloimmune neutropenia. We aimed to determine HNA-1, -3, -4, and -5 frequencies among southern Thais using multiplex PCR and to develop HNA-1 null detection. METHODS: Samples obtained from 427 southern Thai blood donors were genotyped HNA-1, -3, -4,...
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