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Article

Simian immunodeficiency virus infection and immune responses in the pig-tailed macaque testis.

Journal of leukocyte biology - 1 Mar 2015

Winnall Wendy R, Lloyd Sarah B, De Rose Robert, Alcantara Sheilajen, Amarasena Thakshila H, Hedger Mark P, Girling Jane E, Kent Stephen J

Abstract excerpt

The testis is a site of immune privilege in rodents, and there is evidence that T cell responses are also suppressed in the primate testis. Local immunosuppression is a potential mechanism for HIV persistence in tissue reservoirs that few studies have examined. The response of the pig-tailed macaque testis to SIVmac239 infection was characterized to test this possibility. Testes were surgically removed during...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25605872
DOI: 10.1189/jlb.4A0914-438R
PMCID: PMC5477897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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