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Article

Semen CD4+ T cells and macrophages are productively infected at all stages of SIV infection in macaques.

PLoS pathogens - 1 Jan 2013

Bernard-Stoecklin Sibylle, Gommet Céline, Corneau Aurélien B, Guenounou Sabrina, Torres Claire, Dejucq-Rainsford Nathalie, Cosma Antonio, Dereuddre-Bosquet Nathalie, Le Grand Roger

Abstract excerpt

The mucosal events of HIV transmission have been extensively studied, but the role of infected cells present in the genital and rectal secretions, and in the semen, in particular, remains a matter of debate. As a prerequisite to a thorough in vivo investigation of the early transmission events through infected cells, we characterized in detail by multi-parameter flow cytometry the changes in macaque seminal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24348253
DOI: 10.1371/journal.ppat.1003810
PMCID: PMC3861532

Genes

CCR5
CXCR4

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