Article
Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.
Tissue antigens - 1 Nov 2008
Franceschi D S A, Mazini P S, Rudnick C C C, Sell A M, Tsuneto L T, de Melo F C, Braga M A, Peixoto P R F, Visentainer J E L
Abstract excerpt
The aim of this study was to investigate the role of killer cell immunoglobulin-like receptor (KIR) genes in leprosy immunopathogenesis. Genotyping of KIR and human leukocyte antigen (HLA) genes was performed by polymerase chain reaction with sequence-specific oligonucleotide probes in 165 leprosy patients. Both activating KIR2DS2 and KIR2DS3 frequencies were higher in tuberculoid leprosy (TT) patients than in...
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