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Article

Open pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell lines.

Cancer medicine - 1 Mar 2015

Goecks Jeremy, El-Rayes Bassel F, Maithel Shishir K, Khoury H Jean, Taylor James, Rossi Michael R

Abstract excerpt

We describe open, reproducible pipelines that create an integrated genomic profile of a cancer and use the profile to find mutations associated with disease and potentially useful drugs. These pipelines analyze high-throughput cancer exome and transcriptome sequence data together with public databases to find relevant mutations and drugs. The three pipelines that we have developed are: (1) an exome analysis...

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PMID: 25594743
DOI: 10.1002/cam4.360
PMCID: PMC4380965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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