Article
Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.
JCO clinical cancer informatics - 1 Feb 2022
de Bruijn Ino, Li Xiang, Sumer Selcuk Onur, Gross Benjamin, Sheridan Robert, Ochoa Angelica, Wilson Manda, Wang Avery, Zhang Hongxin, Lisman Aaron, Abeshouse Adam, Zhang Emily, Thum Alice, Sadagopan Ananthan, Heins Zachary, Kandoth Cyriac, Rodenburg Sander, Tan Sander, Lukasse Pieter, van Hagen Sjoerd, Fijneman Remond J A, Meijer Gerrit A, Schultz Nikolaus, Gao Jianjiong
Abstract excerpt
PURPOSE: Interpretation of genomic variants in tumor samples still presents a challenge in research and the clinical setting. A major issue is that information for variant interpretation is fragmented across disparate databases, and aggregation of information from these requires building extensive infrastructure. To this end, we have developed Genome Nexus, a one-stop shop for variant annotation with a...
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