Tumor necrosis factor alpha promoter polymorphism and severity of acute kidney injury.

doi:10.1159/000351684

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Article

Tumor necrosis factor alpha promoter polymorphism and severity of acute kidney injury.

Nephron. Clinical practice - 1 Jan 2013

Susantitaphong Paweena, Perianayagam Mary C, Tighiouart Hocine, Liangos Orfeas, Bonventre Joseph V, Jaber Bertrand L

Abstract excerpt

BACKGROUND: Tumor necrosis factor-alpha is a proinflammatory cytokine that has been implicated in the pathobiology of acute kidney injury (AKI). METHODS: We explored the association of a functional polymorphism in the promoter region (rs1800629) of the TNFA gene with severity of AKI, as defined by level of glomerular filtration (serum cystatin C and creatinine) and tubular injury (urinary NAG, KIM-1, α-GST, and...

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Identifiers

PMID: 23796916
DOI: 10.1159/000351684
PMCID: PMC4959276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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