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Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro.

Molecules (Basel, Switzerland) - 10 May 2021

Taki Aya C, Jabbar Abdul, Kurz Thomas, Lungerich Beate, Ma Guangxu, Byrne Joseph J, Pflieger Marc, Asfaha Yodita, Fischer Fabian, Chang Bill C H, Sleebs Brad E, Gasser Robin B

Abstract excerpt

Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthelmintics with distinct mechanisms of action. Extending previous work, here we screened a panel of 245 chemically-diverse small molecules for anti-parasitic activity against Haemonchus contortus-an economically important parasitic nematode of livestock. This panel was screened in vitro...

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PMID: 34068691
DOI: 10.3390/molecules26092819
PMCID: PMC8126080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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