Article
Advances in the macrolides and quinolones.
Infectious disease clinics of North America - 1 Sept 1998
Boswell F J, Wise R
Abstract excerpt
The widespread, frequent clinical use of the macrolides and quinolones has led to resistance in several species. With the prevailing increase of resistance, new developmental compounds with improved spectra, pharmacokinetics, and reduced adverse effects are required, coupled with logical use of t...
Topics
- 4-Quinolones
- Anti-Bacterial Agents
- Anti-Infective Agents
- Bacteroides fragilis
- Chlamydophila pneumoniae
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Genes, Bacterial
- Gram-Negative Aerobic Rods and Cocci
- Gram-Positive Cocci
- Haemophilus influenzae
- Legionella pneumophila
- Macrolides
- Mutation
- Mycoplasma pneumoniae
- Structure-Activity Relationship
