Article
Immune-related pathways including HLA-DRB1(∗)13:02 are associated with panic disorder.
Brain, behavior, and immunity - 1 May 2015
Shimada-Sugimoto Mihoko, Otowa Takeshi, Miyagawa Taku, Khor Seik-Soon, Kashiwase Koichi, Sugaya Nagisa, Kawamura Yoshiya, Umekage Tadashi, Kojima Hiroto, Saji Hiroh, Miyashita Akinori, Kuwano Ryozo, Kaiya Hisanobu, Kasai Kiyoto, Tanii Hisashi, Okazaki Yuji, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
Panic disorder (PD) is an anxiety disorder characterized by panic attacks and anticipatory anxiety. Both genetic and environmental factors are thought to trigger PD onset. Previously, we performed a genome-wide association study (GWAS) for PD and focused on candidate SNPs with the lowest P values. However, there seemed to be a number of polymorphisms which did not reach genome-wide significance threshold due to...
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