Article
Expression profiles of MYC protein and MYC gene rearrangement in lymphomas.
The American journal of surgical pathology - 1 Mar 2015
Chisholm Karen M, Bangs Charles D, Bacchi Carlos E, Molina-Kirsch Hernan, Cherry Athena, Natkunam Yasodha
Abstract excerpt
MYC translocations are a defining feature of Burkitt lymphoma and a group of diffuse large B-cell lymphoma (DLBCL) with inferior outcome. However, the clinical relevance of MYC gene rearrangement and its relationship with MYC protein expression has not been well characterized in lymphomas. Tissue microarrays containing 1214 lymphomas were successfully evaluated by immunohistochemistry using anti-MYC clone Y69 and...
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